Chemistry (Track)



SYNTHESIS OF SOME HETEROCYCLIC NITROGEN COMPOUNDS

Abou-Bakr Haredi Abdel-Monsef Ahmed, M.A. Hassan, A.M.M. Younes and M.M. Taha


South Valley University- Faculty of Science, Egypt

Abstract:

Pyrimidine ring is present in a large number of biologically important compounds such as alkaloids, drugs, agrochemicals or antimicrobial agents and, since the early years of this century, numerous studies on the synthesis and structure-activity relationships of pyrimidine derivatives have been reported [1]. Because of the wide pharmacological applications of pyrimidines and quinazolines, we aimed in this work to synthesize new derivatives of 3-substituted quinazolinediones.

Keywords: Pyrimidine, pharmacological , 3-substituted quinazolinediones.